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Exact Sciences Innovation (formerly Base Genomics) is an epigenetics company based on a new invention to sequence DNA methylation licensed from Ludwig Cancer Research and the University of Oxford. The technology, TAPS (TET-assisted pyridine borane sequencing), sets a new gold standard for DNA methylation detection to measure changes in DNA over time. With greater sensitivity, accuracy and cost-effectiveness than existing techniques, near term applications will include the early detection of cancer through a blood test, and sensitive detection and analysis of minimal residual disease. In scaling the technology, Base Genomics’ leadership team of world-leading scientists, product developers, and clinicians aim to unlock a range of new applications in research and healthcare.

Bioinformatics Scientist/Lead, NGS

Develops novel methodologies & algorithms for methylation analysis. Implements pipelines & tools to ensure timely analysis of NGS data. Work with lab-based teams on experimental design. PhD scientist with significant postdoctoral or Industrial Experience.

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Statistical Geneticist/Bioinformatician, NGS

Develops novel methodologies & algorithms for methylation analysis. Implements pipelines & tools to ensure timely analysis of NGS data. Work with lab-based teams on experimental design. PhD scientist with significant postdoctoral or Industrial Experience.

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Software Developer/Lead Software Developer

We are looking for a Software Developer to lead or drive the creation of software infrastructure enabling the analysis & interpretation of Next Generation Sequencing (NGS) Data generated using TAPS.

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Enzymology & Protein Engineering Scientist

Support the creation, development, characterization of key enzymes. Graduate Scientist with several years of experience, ideally in Industry. Lab-based.

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