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ABOUT THE ROLE

Kyttaro seeks an outstanding, highly driven, and top-performing scientist with experience in peptide synthesis and/or medicinal chemistry to support Kyttaro’s anti-inflammatory drug discovery platform technology program.

 

The successful candidate will:

1) lead the set-up of a biochemical lab facility at the Oxford BioEscalator

2) head the development and synthesis of novel peptide drug combinations using chemical or peptide-nano-particle based approaches

3) supervise Associate Scientists for peptide synthesis

4) work closely with cellular, molecular, structural and computational biologists, as well as immunologists, medicinal chemists and biochemical researchers in a multi-disciplinary environment to create novel biologic compounds with therapeutic and diagnostic application in inflammatory diseases. The individual should be able to lead his/her areas of responsibility, develop novel techniques, collaborate with the broader team, and communicate results across disciplines. The successful candidate will have the opportunity to interact and work with leading scientists and business leaders from premier institutions and to help translate emerging therapeutic ideas into reality.

 

RESPONSIBILITIES:

  • Lead the set-up of a biochemical lab for peptide synthesis and characterization
  • Head the peptide synthesis efforts to support the development of our technology platform, develop appropriate project-related research strategies and monitor progress
  • Design, execute and/or supervise experiments related to the chemical synthesis of novel combinatorial peptide entities and peptide nanoparticle conjugates
  • Identify and develop suitable techniques / experimental protocols for peptide synthesis and characterisation in collaboration with other team members
  • Conduct and/or supervise experiments in a meticulous way and analyse and interpret the data
  • Manage projects from initiation to launch, while balancing multiple project assignments
  • Supervise and manage Associate Scientist for peptide synthesis
  • Maintain accurate experimental records
  • Collaborate closely with academic partners and/or contract research organisations
  • Write reports and present findings to colleagues

 

ESSENTIAL QUALIFICATIONS / SKILLS:

  • PhD in a relevant field including chemical biology, medicinal chemistry, biochemistry or molecular biology
  • Mature and broad skills related to organic peptide synthesis/modifications (e.g. solid and solution phase, linear/cyclic), peptide purification and medicinal chemistry
  • Experience with NMR, chromatographic separation (HPLC, GPC, silica gel), Liquid Chromatography-Mass spectrometry, crystallography and/or other analytical approaches (e.g. SPR) to characterize peptides and their interactions
  • Ability to independently design, execute and interpret scientific experiments
  • Excellent supervising and management skill
  • Experience leading scientific research projects/teams
  • Excellent communication skills, written and oral
  • Ability to work in a fast-paced environment, balancing multiple projects
  • Strong team player with excitement for new challenges and ability to deal with flexibility

 

DESIRABLE QUALIFICATIONS / SKILLS:

  • 7+ years of experience as a postdoc/scientist in an academic or industry laboratory
  • Experience optimizing peptides/peptide combinations that can bind to or inhibit protein function
  • Background with drug discovery, cellular and/or molecular biology in the context of inflammatory diseases or immunology
  • Good knowledge related to phage-display techniques and/or peptide drug discovery and delivery

Job Types: Full-time, Permanent

Salary: From £100,000.00 per year

Additional pay:

  • Performance bonus

Schedule:

  • Day shift

Education:

  • PhD (required)

Work remotely:

  • No

ABOUT KYTTARO

Kyttaro is a UK-based clinical-stage bioscience company focused on developing first-in-class biologic therapeutics treating inflammatory, metabolic, gastrointestinal, and cardiovascular diseases to improve global health and patients’ lives. Kyttaro’s lab is located at the BioEscalator – a world-class launching pad for biotech companies that commercialize technology developed by Oxford University.

Kyttaro is an affiliate of Cambridge Science (CSC), a Boston-based bioscience company with a successful track record of launching and co-founding companies with some of the world’s top Principal Investigators. Apart from Kyttaro, CSC has already launched two emerging life science companies, Vivtex and Ovibio, and will continue to evolve into a diversified biotech company running multiple research and development, clinical, and commercial programs. Through pursuing the venture creation business model, CSC has been able to leverage its top-tier science and network across scientific programs to create a unique value proposition for its shareholders and, ultimately, patients.