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PepGen is hiring

Associate Scientist/Scientist/Senior Scientist, Peptide and Bioconjugation Chemistry

The Associate Scientist/Scientist/Senior Scientist* will be responsible for key aspects of the peptide-nucleic acid conjugate medicinal chemistry for the development of the PepGen pipeline. In this hands-on laboratory position, the successful candidate will drive the discovery and development of novel peptide-nucleic conjugates. This scientist will closely coordinate chemistry activities with biology and non-clinical teams to determine the optimal properties for next-generation nucleic acid therapeutics.  Commensurate with the experience of the candidate, opportunities for leadership in supervising PepGen colleagues and outsource partners may be available.

*Title commensurate with education and experience.

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Senior/Principal Scientist, Analytical Development

The Senior Scientist/Principal Scientist, Analytical Development* will be a key member of the Analytical Development group at PepGen. The successful candidate will lead lab activities associated with method development and analytical support for discovery and development in-house and at contract testing labs. The successful candidate will work very closely with the Head of Analytical Development and QC to develop and validate phase appropriate chromatographic methods, mainly focusing on UHPLC-UV/LC-MS methods for characterization of PepGen´s proprietary enhanced delivery oligonucleotides (EDOs). In addition, this scientist will play a critical role in building a strong analytical development/QC team and shaping analytical CMC strategy for various programs at PepGen.

*Title commensurate with education and experience.

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Senior Director/Director, Preclinical Research

The Senior Director/Director, Preclinical Research, will play an important role in shaping the discovery research and development strategy and in expanding the therapeutic scope of PepGen´s proprietary enhanced delivery oligonucleotides (EDOs).  In addition to providing leadership and guidance to the drug discovery teams at PepGen, the Senior Director, Preclinical Development will work with other functional leads at PepGen to discover and develop first-in-class and best-in-class EDO therapies for neuromuscular diseases and as well as other genetic diseases with profound medical need.

The successful candidate will work closely with the SVPs of Discovery and Chemistry/CMC to design and implement PepGen’s research strategy.  Importantly, the Senior Director, Preclinical Research, will be a key member of cross-functional teams with a mission to build and support preclinical drug discovery and development programs all the way from concept through to IND submission.

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About PepGen:

We are a biotechnology company advancing next-generation oligonucleotide therapies for neuromuscular diseases. Our ambition is to unlock the potential of nucleic acid therapeutics by leveraging the drug delivery capabilities of our proprietary Enhanced Delivery Oligonucleotide (EDO) platform. We are applying this technology across a wide range of indications through independent and partnered development pathways and are rapidly growing our team, especially at our U.S. headquarters in Boston, Massachusetts. To learn more, please inquire at the link below, check out our website or follow us on Twitter and LinkedIn.