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Bioarchitech, Oxford, UK, an immuno-oncology therapeutics start-up company announces that it has secured a material license from the European Collection of Authenticated Cell Cultures (ECACC), UKHSA for a mammalian cell line to be developed as a scalable and high yield viral manufacturing platform and for the vector backbone of BA-V151, a preclinical stage candidate being developed as a treatment for metastatic cancers.

Bioarchitech secures strategic material license with the UK Health Security Agency (UKHSA) to support manufacturing and clinical development of BA-V151

Bioarchitech, Oxford, UK, an immuno-oncology therapeutics start-up company announces that it has secured a material license from the European Collection of Authenticated Cell Cultures (ECACC), UKHSA for a mammalian cell line to be developed as a scalable and high yield viral manufacturing platform and for the vector backbone of BA-V151, a preclinical stage candidate being developed as a treatment for metastatic cancers.

PepGen announces topline results from lowest dose (5 mg/kg) MAD cohort in the ongoing phase 2 FREEDOM2 study demonstrating favourable safety, splicing and vHOT data

PGN-EDODM1 was generally well-tolerated, with all adverse events being mild or moderate, and no serious adverse events reported. The mean splicing correction observed with PGN-EDODM1 (n=6) was 7.3%, compared to 6.8% for the placebo (n=2). Excluding one outlier patient, the treatment group showed a mean splicing correction of 22.9% (n=5). Promising trends were seen in vHOT in the PGN-EDODM1 treated group. The company is on track to report clinical data from the 10 mg/kg multiple dose cohort in the second half of 2026, with sufficient cash expected to fund operations into the second half of 2027.

BioEscalator joins Equinox partnership to drive inclusive growth

The BioEscalator is proud to be a founding signatory of Equinox (Equitable Innovation Oxford), a new initiative connecting research, business and communities to accelerate innovation and deliver inclusive growth in Oxford and the wider region.

Cardiovascular clinical scientist & diagnostic entrepreneur Professor Paul Leeson joins the BioEscalator Management Board

We are delighted to welcome Professor Paul Leeson to our Management Board - an expert in cardiovascular imaging and preventive cardiology, entrepreneur and supporter of translational research and spin-out creation.

Enara Bio to unveil first-in-class DARKFOX-targeting bispecific T cell engager ENA101 in oral presentation at AACR 2026, showcasing breakthrough potential for solid tumour immunotherapy

Enara Bio, a pioneer in Dark Antigen® discovery and bispecific T cell engager innovation, today announced new data to be presented at the American Association for Cancer Research (AACR) Annual Meeting 2026, highlighting its lead clinical candidate, ENA101, a first-in-class bispecific T cell engager (TCE) targeting DARKFOX®, a novel cancer-specific Dark Antigen discovered with Enara’s EDAPT® platform.

BioEscalator Bulletin - Spring 2026

Stay informed with the latest BioEscalator updates, tenant and alumni news in the Spring 2026 edition of the BioEscalator Bulletin.

OSE announces new board appointments

Professor Dame Molly Stevens joins as a Non-Executive Director and University representative. Professor Richard Hobbs also joins as a Non-Executive Director. Simon Boddie, the Chief Financial Officer of the University of Oxford, steps down.

International Women’s Day 2026: Celebrating Success Across the Bioscience Ecosystem

Q: What kind of biosciences event features being an actress, being a cool kid, twin babies, presenting to empty lecture theatres, offices with no toilets for women, and mentorship schemes that don’t work? A: The BioEscalator’s celebration of International Women’s Day 2026.

Let’s just get married – the story of an acquisition

"We decided to skip the engagement and just get married" – that’s how Hutano Diagnostics’ CEO Atherton Mutombwera describes his company’s acquisition by EDx Medical in 2023. The meeting of minds between him and the purchaser’s CEO, Dr Mike Hudson, was the culmination of six years of hard work by Atherton developing multiplex lateral flow diagnostics based on aptamers.

Theolytics awarded €8 million in Horizon Europe 2025 grant funding to advance phase 2 study of THEO-260 in ovarian cancer

Pending final negotiations, the grant will fund up to 20 patients in the OCTOPOD-IV Phase 2a expansion study of THEO-260 in platinum-resistant ovarian cancer. The competitive funding award highlights Theolytics’ innovative science and strong clinical development plan. The application is coordinated with several major international clinical centres and world-class partners.

Infinitopes: Preventing Cancer Recurrence

Infinitopes has been featured in a recent blog post by VC Amplify Partners, highlighting its work to prevent cancer recurrence and its approach to advancing precision cancer vaccines.

U-Ploid Biotechnologies launches collaborative research study with San Diego Fertility Center and Nova Genomics

U-Ploid Biotechnologies has initiated a new collaborative research study with San Diego Fertility Center (SDFC) and Nova Genomics, marking an important translational step in the company’s programme to address the biological causes of age-related infertility.

BiotechTV talks to clinical-stage tenant Infinitopes on its second BioEscalator visit

On its recent visit to Oxford, leading biotech sector commentator Biotech TV had a fascinating and wide-ranging conversation with Dr Jonathan Kwok, the CEO of BioEscalator tenant Infinitopes.

CyanoCapture and Persist AI announce strategic collaboration to build world's first robotic GMP facility for oral protein and peptide drugs

The pioneering partnership combines cyanobacteria-based oral delivery with AI-driven robotics to transform how life-saving biologics reach patients.

Highlighting our award-winning apprentices in NAW 2026

Apprentices are a vital part of BioEscalator life, and we always enjoy celebrating their achievements and impact in National Apprenticeship Week.

Nucleome Therapeutics appoints experienced biotech executive Dr Michelle Morrow as Chief Scientific Officer

Dr Morrow brings deep expertise in immunology, oncology, and pharmacology, with a strong track record of advancing innovative pipelines from discovery to the clinic. The appointment reflects growing momentum at Nucleome following the nomination of the first preclinical development candidate, lead candidate NTP464, which is progressing towards IND-enabling studies.

U-Ploid Biotechnologies appoints Tim Stonehouse as Head of Regulatory Affairs

U-Ploid Biotechnologies (U-Ploid), an Oxford-based biotechnology company pioneering first-in-class therapeutics for reproductive health, today announced the appointment of Tim Stonehouse as the company’s first in-house Head of Regulatory Affairs.

AstraZeneca Exchange launches in Oxford with support for BioEscalator tenants

What started out as an initiative to embed AstraZeneca into Cambridge's ecosystem has turned into a Science and Business Mentoring programme, AstraZeneca Exchange, which has now been launched at the University of Oxford. So far four BioEscalator tenants who will benefit from this valuable scheme have been named - Infinitopes, Spectre Bio, Granza Bio and ISOgenix Limited.

OMass Therapeutics appoints Jonathan Montagu as Chair of the Board of Directors

OMass Therapeutics (‘OMass’ or ‘the Company’), a biotechnology company identifying medicines against highly validated target ecosystems such as membrane proteins or intracellular complexes, today announced updates to its Board of Directors, including the appointment of Jonathan Montagu, Chief Executive Officer and co-founder of HotSpot Therapeutics, as Board Chair.

First Cambridge – Oxford BioVenture Showcase proves a success

The positive feedback from investors and presenting companies at our recent first Cambridge – Oxford BioVenture Showcase with the Milner Therapeutics Institute shows what a success it was. We will certainly be doing it again!

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