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« Back to NewsInfinitopes granted Phase I/IIa Clinical Trial Application approval to evaluate precision vaccine targeting early-stage oesophageal cancer
8 April 2025
Oxford, UK – 9 April 2025 – Infinitopes Ltd today announces that the UK Medicines and Healthcare products RegulatoryAgency (MHRA) has granted Clinical Trial Application (CTA) approval for the first-in-humanPhase I/IIa clinical trial of ITOP1, the company’s lead ‘off-the-shelf’ cancer vaccine.
Care Fertility and U-Ploid Biotechnologies announce research collaboration to improve egg quality in women of advanced maternal age
7 April 2025
OXFORD, England, April 8, 2025 /PRNewswire/ -- Care Fertility, a leading fertility treatment provider, and U-Ploid Biotechnologies, a pioneering reproductive health biotech, today announces a research collaboration aimed at improving egg quality and improve fertility treatment. Egg quality is one of the main contributing factors to infertility and is known to deteriorate rapidly with increasing female age. This research collaboration has the potential to validate novel therapeutics and offer hope to millions struggling to conceive.
Infinitopes strengthens Board with two biotech leaders to advance precision immunotherapies into the clinic
20 March 2025
Infinitopes welcomes Jo Brewer, PhD (CSO at Adaptimmune), and Dan Menichella (former CEO and CBO of CureVac's US subsidiary) as incoming Non-Executive Directors, bringing deep expertise in immunotherpay and oncology innovation.
Entelo Bio ushering in new ways of doing science
12 March 2025
Entelo Bio, a venture backed biotechnology company pioneering the emerging isoform frontier of medicine, releases Flow Agent, an adaptive agentic (autonomous, AI-driven) based workflow management framework for bioinformatics workflows. Fully adopted and extended at Entelo Bio, Flow Agent frees laboratory and computational scientists from repetitive workflows, enabling greater focus on biological interpretation.
OXcan President and Co-Founder features as guest speaker on TheHill Digital Innovation Podcast
19 February 2025
Andreas Halner, president and co-founder of Oxford Cancer Analytics (OXcan), who chats to our director, Megan Morys-Carter, about the company's inception, what makes the technology so revolutionary and the ever increasing success OXcan have been met with recently.
New ‘Super Test’ for prostate cancer developed in the UK by EDX Medical
17 February 2025
CAMBRIDGE, England--(BUSINESS WIRE)--Scientists in Cambridge have developed a new ‘super test’ for prostate cancer in an effort to revolutionise screening and diagnosis of the disease and accelerate personalised treatment for patients.
U-Ploid Biotechnologies announces the appointment of Professor Alison Campbell to its advisory board
15 January 2025
U-Ploid, a venture-backed biotechnology company developing next-generation fertility therapeutics, is pleased to announce the appointment of Professor Alison Campbell to its Advisory Board. In this key role, Professor Campbell will provide strategic guidance on company research programmes, working closely with the U-Ploid team to drive innovation in fertility treatments.
Oxford Cancer Analytics raises USD$11M in series A funding to transform early lung cancer detection and enable curative treatments
9 January 2025
Dr. Heinrich Roder, expert in lung cancer proteomics liquid biopsy, appointed as Senior Vice President of Research and Development at OXcan.
AI-powered cancer immunotherapy discovery could be a step closer
28 November 2024
TechBio startup, Exogene, is leveraging artificial intelligence (AI) to develop innovative immunotherapies with the potential to eliminate untreatable solid tumours in cancer patients. Through a collaboration with German company Alithea Bio, Exogene hopes to speed up cancer immunotherapy discovery and make it more cost-effective.
Infinitopes to showcase breakthroughs on cancer vaccine development at SITC 2024: Insight into a double-blind, Phase I/IIa clinical trial
8 November 2024
Infinitopes, an integrated cancer biotech combining world leading platforms in precision antigen discovery with vaccine vectors capable of durably stimulating protective immune responses, today announces that it will be presenting three posters on its pioneering cancer vaccine discovery and development, including one that has been recognised as a ‘top 100’ poster presentation, at the Society for Immunotherapy of Cancer (SITC) 2024, held in Houston, US, from 6-10th November.
Eterna Biologics: Revolutionising RNA therapeutics
28 August 2024
We are excited to welcome Eterna Biologics, a University of Oxford biotech spinout company with a mission to unleash the full potential of RNA medicines. The company aims to enhance global health by expanding the applicability of RNA-targeting medicine to develop treatment for a wide range of human conditions.
Evolvere Biosciences accepted into the prestigious Y Combinator program
23 August 2024
The team of University of Oxford students is making strides that could transform our approach to antibiotics.
U-Ploid thrilled to join the BioEscalator Community
21 August 2024
U-Ploid Biotechnologies joins the BioEscalator to develop groundbreaking therapeutics that improve egg quality and revolutionise IVF.
RE-AIM Therapeutics: Targeting disease causal cells to cure autoimmunity
18 July 2024
We are delighted to welcome RE-AIM Therapeutics to the BioEscalator community, a start-up focused on developing antibody-based curative therapies for inflammatory disorders, such as psoriasis and inflammatory bowel disease.
The BioEscalator welcomes SiGenex to its growing community
18 July 2024
SiGenex is advancing genomic medicine with its innovative, artificial intelligence-powered in-hospital sequencing platform. The company's technology is designed to transform how hospitals, clinics, and medical centres perform targeted next-generation sequencing (NGS) tests.
Granza Bio grabs $7M seed from Felicis and YC to advance delivery of cancer treatments
2 July 2024
In April 2024, the BioEscalator welcomed Granza Bio, a biotech startup focusing on developing novel immunotherapy delivery methods. The company has already attracted investor interest and closed a successful $7.14 million seed funding round led by Felicis and Refactor, with participation from Y Combinator.
Integrated cancer biotech Infinitopes secures £12.8M seed financing to enhance its Precision Immunomics(TM) antigen discovery technologies to target five more cancers
30 April 2024
Funding also supports the start of phase I/IIa study for lead vaccine, ITOP1
Granza Bio: Pioneering personalised and targeted cancer therapeutics
3 April 2024
The BioEscalator is pleased to welcome Granza Bio, a biotech startup founded by two PhD graduates in oncology and immunology from the University of Oxford. Granza Bio is pioneering a new era in cancer therapeutics by developing personalised and targeted cancer treatments using the body's own immune system.
Infinitopes has a double victory at the 15th Annual OBN Awards 2023
23 November 2023
The OBN Awards recognise companies that demonstrate outstanding leadership, innovative practices, and significant contributions towards addressing clinical needs at different stages of development.
Hutano Diagnostics acquired by EDX Medical Group
28 September 2023
We are delighted that BioEscalator resident start-up Hutano Diagnostics has announced its acquisition by Cambridge, UK-based EDX Medical Group PLC.