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Enara Bio strengthens senior leadership with key Executive and Board appointments alongside acceleration of multiple T-Cell engager programs

Stacey Davis appointed as Chief Business Officer and Chief Financial Officer. Clive Wood, Ph.D., joins the Enara Board as Non-executive Director.

Orfonyx Bio – big ambitions in protein upregulation

Orfonyx Bio is looking to make its mark as a leader in protein upregulation for clinical benefit – and has made technical progress towards this goal over the past two years. In that time as a BioEscalator tenant the University of Oxford spin-out has also grown from two to seven employees, raised an Oxford Science Enterprises-backed seed round and started to understand where its approach might have the greatest clinical impact. Now it’s raising additional funding.

Infinitopes granted Phase I/IIa Clinical Trial Application approval to evaluate precision vaccine targeting early-stage oesophageal cancer

Oxford, UK – 9 April 2025 – Infinitopes Ltd today announces that the UK Medicines and Healthcare products RegulatoryAgency (MHRA) has granted Clinical Trial Application (CTA) approval for the first-in-humanPhase I/IIa clinical trial of ITOP1, the company’s lead ‘off-the-shelf’ cancer vaccine.

Care Fertility and U-Ploid Biotechnologies announce research collaboration to improve egg quality in women of advanced maternal age

Care Fertility, a leading fertility treatment provider, and U-Ploid Biotechnologies, a pioneering reproductive health biotech, today announces a research collaboration aimed at improving egg quality and improve fertility treatment.

Dr Mary Vinson joins the U-Ploid as Clinical Development Advisor

Dr Vinson brings over 25 years of invaluable experience in the pharma and biotech industry, with a proven track record of leading and contributing to breakthrough therapeutics.

PepGen announces appointment of two new directors to its Board

The company announced the appointments of Lisa Wyman and Mitchell H. Finer, PhD, to its Board of Directors.

Moa named one of TIME's top greentech companies in 2025

Moa recognised as leading global innovator in environmental impact.

Moa forms new biological partnership with NAICONS

Oxford-based agricultural biotech firm Moa Technology has stepped up the global hunt for a safe, effective and affordable biological herbicide by forming a new partnership with NAICONS, an Italian natural products company.

Infinitopes strengthens Board with two biotech leaders to advance precision immunotherapies into the clinic

Infinitopes welcomes Jo Brewer, PhD (CSO at Adaptimmune), and Dan Menichella (former CEO and CBO of CureVac's US subsidiary) as incoming Non-Executive Directors, bringing deep expertise in immunotherpay and oncology innovation.

The Gender Advantage: Building Inclusive and Thriving Ventures

To celebrate International Women's Day 2025, the BioEscalator was delighted to host a double panel discussion and networking event with EnSpire Oxford and Advanced Oxford.

Entelo Bio ushering in new ways of doing science

Entelo Bio, a venture backed biotechnology company pioneering the emerging isoform frontier of medicine, releases Flow Agent, an adaptive agentic (autonomous, AI-driven) based workflow management framework for bioinformatics workflows.

BioEscalator Bulletin - Spring 2025

Stay updated with the latest BioEscalator updates, tenant and alumni news, and upcoming events in the Spring 2025 edition of the BioEscalator Bulletin.

OMass Therapeutics appoints Birgitte Volck as Non-Executive Director

Oxford, United Kingdom – 26 February 2025 – OMass Therapeutics (‘OMass’ or ‘the Company’), a biotechnology company identifying medicines against highly validated target ecosystems such as membrane proteins or intracellular complexes, today announces that Birgitte Volck MD, PhD has joined its Board as a non-executive director.

OXcan President and Co-Founder features as guest speaker on TheHill Digital Innovation Podcast

Andreas Halner, president and co-founder of Oxford Cancer Analytics (OXcan), who chats to our director, Megan Morys-Carter, about the company's inception, what makes the technology so revolutionary and the ever increasing success OXcan have been met with recently.

Enara Bio embarks on a research collaboration with George Washington University to deepen understanding of Dark Antigen® biology and expression

Collaboration may inform future combination strategies that can maximise the efficacy of Enara Bio’s pipeline of TCR-based immunotherapies targeting Dark Antigens®

New ‘Super Test’ for prostate cancer developed in the UK by EDX Medical

CAMBRIDGE, England--(BUSINESS WIRE)--Scientists in Cambridge have developed a new ‘super test’ for prostate cancer in an effort to revolutionise screening and diagnosis of the disease and accelerate personalised treatment for patients.

BioEscalator Bulletin – Annual Review 2023/24 launched

The BioEscalator is delighted to have launched its inaugural Annual Review, ‘Driving innovation, advancing human health ’. It provides for the first time a discussion of our achievements in 2023/24, plus the milestones from our initial five years of operation.

Enara Bio listed in the inaugural edition of The Sunday Times 100 Tech 2025

The guide showcases Britain's fastest-growing private tech companies from The Sunday Times, commercialising innovation across the UK. "This recognition is a testament to our innovative science and the hard work of our incredible team as we strive to develop safe and effective treatments for cancer patients." Enara Bio

U-Ploid Biotechnologies announces the appointment of Professor Alison Campbell to its advisory board

U-Ploid, a venture-backed biotechnology company developing next-generation fertility therapeutics, is pleased to announce the appointment of Professor Alison Campbell to its Advisory Board. In this key role, Professor Campbell will provide strategic guidance on company research programmes, working closely with the U-Ploid team to drive innovation in fertility treatments.

Oxford Cancer Analytics raises USD$11M in series A funding to transform early lung cancer detection and enable curative treatments

Dr. Heinrich Roder, expert in lung cancer proteomics liquid biopsy, appointed as Senior Vice President of Research and Development at OXcan.

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